POINT-OF-CARE
DIAGNOSTIC TESTING
Point-of-Care Diagnostic Testing known in the industry as
laboratory in your hand has evolved in the last decade allowing for immediate
diagnostic testing at the patient’s bedside, but a new study points to perhaps
some usages and healthcare benefits not previously realized such as in the emergency room. Welcome to
The Clinicians Roundtable on ReachMD XM 157, The Channel for Medical
Professionals. I am Bruce Japsen, the healthcare reporter of the Chicago
tribune and with me today is Dr. Peter Farrell, the DivisionalVice President of marketing and clinical
affairs by Abbott Laboratories Point of Care. Mr. Farrell joined Abbott Point
of care in March of 2005 and he brings with him several decades of healthcare
experiences in the pharmaceuticals, diagnostic, medical imaging, and biotech
industry. Working with Abbott for 5 years and BioChem Pharma, started up
public imaging company.
BRUCE JAPSEN:
Peter Bell welcome to ReachMD XM 157, The Channel for
Medical Professionals.
DR. PETER FARRELL:
Thanks Bruce.
BRUCE JAPSEN:
Well, we know in healthcare, one of the most expensive
settings for class is the emergency room and what you are talking about is that
this point of care testing business and if you could tell us little bit about
that, but also how this is going to be effective in the emergency room?
DR. PETER FARRELL:
Sure. First of all, the
Abbott Point of Care Division of Abbott Laboratories has an analyzer called the
i-STAT. There have been significant trends and changes in the emergency
department across the country in the United States and lot of them are driven by
the medical treatment and labor act from 1986 which allows people to be
screened and treated in the emergency medical from emergency medical conditions
without any discriminations and this really made the ED a primary spot for
people to go to get care and the emergency departments have 3 goals. One is
triage are the patients they want to treat them quickly and safely and then
they want to make sure that they are working efficiently. And what we see and
what some of the data points to is that there is some key matrix in the
emergency department that people need to be aware of and our point of care
testing device in the emergency department, the i-STAT can help with some of
those things. So, when you look at an emergency department is really couple of
key matrix that people for. It is overcrowding and there is lots of evidence
of that showed a number of EDs in the United States has declined and certainly
the number of people that are visiting emergency rooms annually has gone up
dramatically. There is also the boarding where people are in the emergency
department but they do not have a bed for them to go to, so they stay in the
hall, they stay in close proximity to the emergency department. They cannot be
dispositioned throughout the hospital and the last one is just diversion, which
is the number of ambulance visits, that show up, to the emergency
department, but there is no space in the emergency department and the ambulance
has to drive to another emergency room to be able to treat that patient. So, there
is clearly something you read and see in the paper and the public all the time
that our driving care and changes in the emergency department.
BRUCE JAPSEN:
And so when you think about also the rising number of
uninsured, I mean 45 million of uninsured people and there is a huge number of
them that show up into the emergency room that if you have devices of any kind
that can triage these people and get them to the right place at the right time,
it could save some dollars and potentially some lives. If you could perhaps
walk us through some examples on this with this device?
DR. PETER FARRELL:
First of all, I would just like to state you are absolutely
right and that there are many uninsured people that are showing up to the
emergency department because that is their only source of real care and
emergency departments are certainly aware of that and as it relates to cardiac
care for example, where the main issue that is seen in the emergency department
are chest pain and shortness of breath. The emergency department has started
to transition to different ways. They have transitioned to have chest pain
centers and different observation units, so that they can actually start to
categorize their patients better and put them in units where they can observe
them and not keep them in the emergency department, that has become quite
popular in the United States to be able to make sure that you are putting those
chest pain patients into the right level of care so that you can move them
either through the hospital or out of the hospital efficiently. So, with those
tools and those observation in heart centers, they have started to specialize
in care, which then has allowed more beds to be available for general sick
people that come into the emergency department.
BRUCE JAPSEN:
If you could give us an idea how many beds frees up, what
kind of savings, or other data points that you saw on the study?
DR. PETER FARRELL:
Yeah, I will. Specifically in the study what we are looking
at is it was done through the University of Cincinnati with other affiliated
academic centers that were part of it and there are 2000 patients in this
randomized control clinical trial went on over 2 years and what some of the
data that we were able to see from this is that it really did have an impact
doing point of care testing. It did have an impact on the discharge of
patients when you looked at testing being done in the central laboratory versus
being done at the patient’s bedside. So, one of the most important things is
that there are some guidelines that have been established for ACS or cardiac
testing to get your troponin test done within 60 minutes preferably within 30,
but mandated within 60. This is an AHA guideline and almost 97% of the case of
Point of Care was able to meet that 60-minute turn around time where it was
less than 50% with the central laboratory. And so what we are able to see is
that the treatment decisions were actually sped up by almost 20 minutes with
the use of the i-STAT Point of Care device.
Well, if you are just joining us or even if you are new
to our channel you are listening to The Clinicians Roundtable on ReachMD XM
157, The Channel for Medical Professionals. I am Bruce Japsen, the healthcare
reporter with the Chicago tribune and joining me today is Peter Farrell who is
the Divisional Vice President at Abbott Laboratories Point of Care Business who
joined this from their offices in New Jersey and we are talking about these new
kinds of test Point of Care, which are essentially laboratory in a doctor’s
hands to test patients. We are just talking about the benefits of this, or the
potential benefits if you will in hospital emergency room
BRUCE JAPSEN:
Mr. Farrell, if you could tell us how these tests are used
and some examples of where the care, what kind of care is given to them,
likewise?
DR. PETER FARRELL:
Sure, well traditionally, these types of testing will focus
on cardiac markers or those tests that are done in the emergency department,
general chemistries, or cardiac test as a predominant one. They have been
traditionally done in the laboratory setting, which means that the sample be
collected from the patient and somehow they will get down to the laboratory,
the tests will be run, and then the information will be sent back to the
emergency department. The use of the i-STAT system, it changes the dynamics of
how patient care is administered because you are able to get the results within
2-10 minutes. So, with 2 drops of whole blood into a cartridge within 2-10
minutes, the healthcare professionals have the results to be able to make
quicker decisions about what to do with that patient.
BRUCE JAPSEN:
And what kind of diagnosis will they be given and what you
would diagnosis somebody if that would need to be sped to certain department
right away?
DR. PETER FARRELL:
Well, I think that the most obvious is what we read in the
paper everyday and that is for those people that are suffering from chest pain
whether or not, they are having a heart attack and the use of cardiac markers
along with other tools to be able to diagnose up to 10% of all people that enter
into an emergency department have chest pain. So, differentiating whether the
person is having a heart attack is done on a lot of patients but it is also
critical because those heart attack patients, the longer their heart muscle is
being damaged because of lack of blood flow to the heart muscle the more likely
they are to have event to either cause death or permanent heart injury.
BRUCE JAPSEN:
And according to the study, you had said that the patients
were treated and discharged by hospital as much as 44 minutes faster than those
whose lab tests were evaluated by a standard lab. Whether there any sort of
data points in the study where they looked at patient outcomes or anything like
that?
DR. PETER FARRELL:
The patient’s outcome would be a landmark study at that
time. It has been elusive to many different people trying to monitor many
different disease states; it is very difficult to do. So, there was not really
any thing as relates to the patient outcome, but certainly what we have been
able to find is that there were really 4 key findings from the study. The
first was the decease in time for disposition and that was up to 20 minutes
faster using a Point of Care device. Then there was the finding of being able
to meet the guidelines almost 98% of the time of point of care versus just 53%
of the time when it was done in the central lab. The third was the length of
the stay, which you mentioned and reduction between 22-44 minutes. In these
cases that equate to almost 60 hours of bed space monthly, which could be
significant because each day, a bed is occupied in the emergency department
would cost the institution or the providers somewhere between 3-4 thousand
dollars.
BRUCE JAPSEN:
Especially at a teaching hospital where they are supposed to
caring for the sickest patients and their costs are a lot higher. If you can
get people in and out of the teaching hospital quicker and to the right place
for less acute condition, the potential for money saving is probably huge.
DR. PETER FARRELL:
Yeah Bruce you really did hit on what the advantage of point
of care testing is. It is to not only make a quicker diagnosis to a patient
who is sick to get him to the right place whether it would be the cath lab or
to have open heart surgery or to move them on to the ICU, if they are septic to
be able to diagnose that, but it is also to be able to get the patients that
aren’t really sick out of the emergency department so that they are not taking
a bed space for somebody who is sick.
BRUCE JAPSEN:
And what about the adoption of this? Is this primarily with
these type of devices, are they being used predominantly in the hospital and
nursing home, I means they do more need to be used in the emergency room? Is
that sort of a new area?
DR. PETER FARRELL:
I think what the menu in the evolution of cardiac testing is
that there is more point of care testing now starting to be used in the
emergency department to follow guidelines. This has been widely used in the
ICUs and other places of the hospital, the NICUs, to do blood gases for many
years, but as the menu expands and the i-STAT menu is very expensive, does
blood gas testing, chemistry testing, coagulation, and cardiac markers. It
really does provide you the flexibility to check on many different disease
states of a patient very quickly and all there you really do to have a lab in
your hand.
BRUCE JAPSEN:
And also do you see just looking down since you brought it
up the potential evolution of these type of devices to test are, you talked
about various cardiac markers, if you will look into the future and see
potentially what other tests you think these devices could do?
DR. PETER FARRELL:
Well, I think quite frankly, any test that you can use the
results within 10 minutes to be able to make a better diagnosis of a patient’s
disease state could be a test that could be added to the menu of the i-STAT
system. It really is that simple. Think about a test that needs to be done
quickly and that is the type of test that would go on the i-STAT device.
BRUCE JAPSEN:
Well with that I would like to thank Peter Farrell, the
vice president at Abbott Laboratories Point of Care Business who has been our
guest. We have been talking about diagnostic testing and point of care testing
that gives both in and out of the hospital emergency room faster or at least
that ends all. I am Bruce Japsen, the health care reporter of the Chicago
Tribune. I would like to thank Peter Farrell who has been our guest and you
have been listening to The Clinicians Roundtable on ReachMD XM 157, The Channel
for Medical Professionals. If you have comments or suggestions about this or
any other show, please call us at 888MD XM 157 and I would like to thank you
today for listening.
You are listening to ReachMD XM 157, The Channel for Medical
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Influenza Division.
DR. JOSEPH RAZI:
In this week’s influenza update, we will mark the
traditional start of CDCs influenza surveillance year. While CDC conducts
surveillance for influenza year round, the first week of October marks the
point when CDC begins the post weekly updates of national influenza activity on
our website. During this last week, low levels of influenza activity had been
observed in the country. Only 7 states reported sporadic influenza activity
while 41 states and the District of Columbia reported no activity. Less than
1% of the specimens tested in the surveillance laboratories were positive this
last week and the proportion of death attributed to pneumonia and influenza and
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pediatric influenza associated deaths, which is now nationally notifiable
disease. In this report, CDC highlights that while pediatric influenza deaths
are uncommon, the proportion of those deaths among children could also have a
Staph aureus co-infection increased during the 3-year period from 2% in
2004-2005 influenza season to 30% in the 2006-2007 season. Physicians are
asked to suspect Staph aureus pneumonia in patients presenting with influenza
who also have severe respiratory symptoms and also suspect co-infection in
patients with a history of Staph skin infection and severe respiratory
illnesses. The full recommendations as well as surveillance data from CDC can
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